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As expected, BM ADO concentrations showed substantial inter-patient variability, consistent with previous reports describing wide fluctuations among MM patients ( Table 2 Individual patient values for ADO and INO concentrations in bone marrow and peripheral blood at baseline (pre-start) and at DARA treatment failure

[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Feinberg J.I., Bakulski K.M., Jaffe A.E., Tryggvadottir R., Brown S.C., Goldman L.R., Croen L.A., Hertz-Picciotto I., Newschaffer C.J., Fallin M.D., et al

There are other limitations in this study that also need to be noted

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Step sequence is a critical gait parameter of unilateral 6-OHDA Parkinson's rat models