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Similarly, the quinolinium containing parent analogue 1-MQ also lacked passive diffusion properties (Table 1), suggesting that the lipophilicity and drug-like permeability properties of analogues within the methylquinolinium series had to be improved via chemical modification

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These findings aid the development of novel NNMT inhibitors

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This water-soluble vitamin plays a crucial role in energy metabolism, red blood cell production, and neurological function