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10.1007/s11682-018-0029-4 Brain Imaging Behav

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(2012) Long-term behavioral, electro-physiological and neurochemical monitoring of the safety of an experimental antiepileptic implant, the muscimol-delivering Subdural Pharmacotherapy Device (SPD), in monkeys

On the whole, plant host genes specifically affected under virus and viroid infections are related with carbohydrate transport, cell cycle regulation, DNA binding, DNA repair and recombination, DNA replication, glutathione binding, lipid metabolism, microtubule-based movement, oxidation-reduction proteins, OXPHOS activity, programmed cell death regulation, protein domain specific binding, protein folding and processing, regulation of hydrogen peroxide metabolism, senescence as well as signal transduction (with hormone signaling, highlighting relevance of JA signaling in host antiviral defence, e.g., Tan et al., 2022

In a 12-week study in NAFLD patients, every-other-weekly administration of up to 100 mg BFKB8488A, the highest adequately tolerated dose, reduced liver fat by about 40%, serum triglycerides and Pro-C3 by up to 25 to 30% from baseline, while increasing adiponectin by up to 40% and HDL-cholesterol by up to 20% (301)