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NAC might actually act as a pro-oxidant and might lower GSH and increase the amount of oxidized GSH

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In primary rat hippocampal neurons, changes to endogenous APP cleavage and the abundance of CTFs were once again observed upon RABGAP1 KD (Appendix Fig

The identification of alternative targets of HIF hydroxylases is important in order to fully elucidate the pharmacology of hydroxylase inhibitors (PHI)