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Angiogenesis, collagen synthesis, neuroprotection and inflammatory modulation compounds verified for preclinical research Tissue repair is a coordinated biological process involving angiogenesis (the formation of new blood vessels), fibroblast migration, collagen synthesis, and the modulation of the inflammatory response

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Thus, the side chain of Arg439 of IRAP was estimated to interact with the tetrazole ring of the inhibitors while one of the oxygens of the sulfonamide function binds to the zinc ion of the enzyme

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The column was washed with 50 mM Tris-Cl, pH 8.0 and 250 mM NaCl