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Patients with systemic sclerosis and mixed connective tissue disease may also develop a rare but distinct myositis subtype identified as brachio-cervical inflammatory myopathy, characterized by weakness of proximal muscles of the upper limbs and cervical flexor and extensor muscles (108

IHC was contributed by THD

This specific mechanism of action places SS-31 in a class of its own: it is not a signaling peptide acting through cell-surface receptors, but a membrane-targeted therapeutic that physically restores mitochondrial architecture

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Acknowledgements This research was supported by a grant from Tehran University of Medical Science

You will not need to disclose peptide use to the testing laboratory