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IDO-positive cancer patients often exhibit high expression of inhibitory MDSCs, which inhibit T-cell activation and facilitate FOXP3 + Tregs differentiation and activation through the production of kynurenine [467, 805, 806]

Mitochondrial peroxiredoxins

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J Mol Med 103 , 899911 (2025)

2009, Christian-Albrechts-University, Institute of Animal Breeding Rosengren KJ, Daly NL, Fornander LM, Jnsson LM, Shirafuji Y, Qu X, Vogel HJ, Ouellette AJ, Craik DJ: Structural and functional characterization of the conserved salt bridge in mammalian paneth cell -defensins: solution structures of mouse cryptdin-4 and (E15D)-cryptdin-4