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A sterile, 2-0 black braided silk thread was placed around the cervix of the lower left first molar and knotted mesially according to Lohinai et al

Crossing these Jnk1 LoxP/LoxP / Jnk2 -/- mice with Alb-Cre mice produced Jnk hepa ( Jnk hepa mice developed higher liver injury than wild-type animals after APAP overdose, suggesting a beneficial role for combined Jnk1 and Jnk2 activation in hepatocytes during APAP-induced hepatotoxicity

NADPH oxidase 4 (NOX4), a ROS-producing enzyme, is highly expressed in the livers of NASH patients and contributes to pathological inflammation and fibrosis in a mouse model of diet-induced NASH (94)