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Quercetin (Qu), a plant-derived flavonoid, is known for its anti-tumor and anti-proliferative activities

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Mesial temporal lobe epilepsy (MTLE), often accompanied by hippocampal sclerosis (HS), is characterized by severe neuronal loss and glial proliferation in the hippocampus (229, 230)

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The RNA sequence and gene set enrichment analysis revealed the downregulation of the type I interferon (IFN-I) pathway in MPTP-induced mice, which was then counteracted by the overexpression of miR-218-5p

They also proposed that aspartame may contribute to oxidative stress and the release of cortisol