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Our approach is fundamentally different

The dynamic exclusion time was set to 20 s and the peptide match and isotope exclusion functions were enabled

Finally, post-translational hydroxylation of eukaryotic release factor 1 (eRF1) by oxygen-sensitiveJMJD4 (Jumonji domain-containing 4) (Box 2) is required for efficient translation termination rates during normoxia 48 , and during hypoxia, decreased eRF1 hydroxylation leads to inefficient termination (Figure 2)

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Your care plan may also include pelvic floor therapy, lifestyle changes, sexual counseling, partner communication, oral medication, a vacuum device, or other approaches based on your medical history