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And that brings us back to the central question

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Curcumin supplementation can ameliorate oxidative stress levels (MDA and TAC) in postmenopausal women and lower inflammatory biomarkers (hs-CRP) (Table 2) (119)

However, copper overload can inhibit the activity of these enzymes and deplete GSH, a key non-enzymatic antioxidant, leading to decreased GSH levels and reduced antioxidant enzyme activity (126,127)