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Importantly, donor cells were fully MHC-mismatched, suggesting that this strategy could overcome this major hurdle to successful HCT

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Thus, iron availability not only responds to hypoxia but also actively regulates the hypoxic response, highlighting the bidirectional link between iron metabolism and HIF signaling

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A serum B12 test (and ideally methylmalonic acid or homocysteine if your B12 is borderline) gives you a real answer rather than a guess

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