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2021;10(1): e259

The data indicated that more cells in keloids underwent pro-senescence regulation

Systemic (Subcutaneous Injection): This is one of the most common methods used in animal studies

This was achieved by maximizing the activity of reactions that are associated with upregulated genes and minimizing flux through reactions that are downregulated in a condition, while simultaneously satisfying the stoichiometric and thermodynamic constraints embedded in the model using linear optimization 44,81