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Phentermine-specific contraindications include use with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping an MAOI, hyperthyroidism, glaucoma, advanced cardiovascular disease, and history of substance misuse

Therefore, serum B 12 values above the cut-off point of deficiency do not necessarily confirm adequate B 12 status

While standard serum blood tests often fail to capture functional, tissue-level deficiencies, empirical treatment trials have shown profound benefits

+ Thiamine- B1 Serves as a catalyst in carbohydrate metabolism

Advantages : Allows for the delivery of higher doses in a single injection, reducing the need for multiple injections

10.1016/j.celrep.2016.07.027 135 SunW.ZouY.CaiZ.HuangJ.HongX.LiangQ.et al (2022)