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Melatonin further reinforces insulin sensitivity by synchronizing circadian insulin secretion, improving mitochondrial efficiency in hepatocytes and skeletal muscle, and attenuating the nocturnal cortisol overshoot typical in PCOS (226, 227)

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P487 Possible envolvement of the endocannabinoid system in the altered mineralization process in mandibolar bone fibrous dysplasia F

Abnormal ATP7B protein also results in decreased incorporation of copper into ceruloplasmin

Busch et al

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