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Although patients on pregabalin therapy showed an earlier onset of therapeutic effect as compared to oxcarbazepine, the efficacy of the two drugs was found comparable during the 12 weeks of the follow-up period of the study [48]

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(3) The observed decrease in carnitine and CPT I expression in cardiac tissues by SUN was parallel to the increase in cardiac index, cardiac enzymes and myocardial fibrosis which may point to the possible contribution of carnitine deficiency and the inhibition of CPT I as possible mechanisms in SUN-induced cardiotoxicity

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The effects of L-Carnitine supplementation in muscle cramp patients were studied in the Clinical Neuropharmacology journal (Bachman et al., 1996)