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doi: 10.1021/bi100517x

PMID:33667417 Goldenberg, R.M., et al

Pro-EGCG greatly slows down the development, growth, and formation of new blood vessels in experimental endometriosis, showing that it can both protect cells from damage and stop the growth of new blood vessels (131)

We speculate that the peroxynitrite production by misfolded metallated SOD1 may benefit, similarly to the HO formation, by the ability of SOD1 enzyme to accept ubiquitous biological thiols as an alternative substrate for cooper activation

Buffers containing strong chelators (EDTA, EGTA) or reducing agents (DTT, -mercaptoethanol, TCEP) should be avoided at the reconstitution step, since chelators can strip copper from the GHK-Cu component