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With the exception of acetylation, methylation and fatty acid conjugation, the strategy of phase II biotransformation is to convert a xenobiotic to a more hydrophilic form via the attachment of a chemical moiety which is ionizable at physiological pH

Future directions Due to the imperfect therapeutic efficacy and the extremely high costs associated with current treatments, there is a pressing need for novel therapeutics

NLX-112 has shown an acceptable safety profile in a small phase 2a, double-blind trial in 27 PD patients [139]

Glutathione is a master anti-oxidant and detoxifier that cleanses the skin from pollutants

Mart-Carvajal AJ, Gluud C, Arevalo-Rodriguez I, Mart-Amarista CE