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Techniques for conjugating such therapeutic moiety to antibodies are well known, see, e.g., Arnon et al., Monoclonal Antibodies For Immunotargeting Of Drugs In Cancer Therapy, in Monoclonal Antibodies And Cancer Therapy, Reisfeld et al

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HM30-tesirine-treated animals received three doses of 1.5 mg/kg on days 0, 7 and 14 via an i.p

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Our research also verified that decreased expression of GCLM was responsible for the decreased activity of GCL, and that GCL activity was enhanced after the resumption of GCLM to promote GSH synthesis, which directly retarded ferroptosis