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focusing not only on lifespan (total years lived) but also healthspan (the years lived in good health)

Although uncommon, serious adverse effects have been reported

Sin embargo, es importante no hacerlo, ya que son totalmente diferentes

Although they should help to optimize the care of individual patients and assist decision making by basing clinical practice on scientific and medical knowledge the guidelines should not substitute well-informed, prudent clinical practice

Thus giving you energy to combine lifestyle modifications such as exercise and diet

3 Clinical Outcomes in ALS The US Food and Drug Administration (FDA) provides guidance on important outcomes in ALS clinical trials, such as mortality, functional status, respiratory and strength measures, and patient-reported outcomes [27]