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While there is limited information on how other NF-B signaling intermediates affect T cell metabolism, some studies suggest a link between NF-B signaling and mTOR in regulating metabolic changes critical for T cell differentiation (197, 198)

Because of the latter, symptoms of vitamin B deficiency almost always include fatigue

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The severity and timing of these side effects can vary based on individual genetic factors, specific chemotherapy plans, and the total amount of drugs used [3]