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The primary mechanism of action of these drugs in the treatment of vitiligo is calcineurin inhibition, which causes the transcription of several proinflammatory cytokines essential to the pathophysiology of the early immune response to be disrupted and antigen-specific T-cell reactivity to be downregulated 26

These neuroprotective effects offer promising therapeutic strategies for neurodegenerative diseases, particularly AD (Yang et al., 2023)

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et al., 2010, Ringseis et al., 2018, Steiber et al., 2004)

They cost $59 for a one-month supply or $55 per month if you subscribe