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The conclusion of targeted genes studies is the plurality of dysregulated mechanisms as a cause or consequence of epigenetic modifications

BMC Infect Dis 21(1):616 Carr AC, Vlasiuk E, Zawari M, Scott-Thomas A, Storer M, Maze M, Chambers ST (2023) Low vitamin C concentrations in patients with community-acquired pneumonia resolved with pragmatic administration of intravenous and oral vitamin C

The quantitative EPR analysis revealed the concentration of Asc radical to be 1.95 0.1 nM/1 mg brain tissue compared to 0.92 0.1 nM/1 mg brain tissue measured in the reference sample

So far, estimations of this all-important parameter have relied on the use of destructive methods which cannot discriminate between cellular compartments and display significant reproducibility shortcomings

However, the erythema spontaneously disappeared within 30 min after the application