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It corresponds to the last 15 amino acids of human growth hormone (positions 177-191) with an extra tyrosine added at one end to stabilize the molecule

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The efficacy of ADCC and CDC, and consequently response rates observed in GEN501 and SIRIUS trials, are directly proportional to CD38 expression levels on MM cells

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I can understand this because, although I try to be guided by evidence, I tried many things myself which did not have the best evidence backing them up, but when you're up against the wall, all options go on the table