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Insulin-like growth factor-1, as discussed earlier, has implications on lipid and glucose metabolism [87, 88], and its exogenous administration enhances insulin sensitivity in healthy adults [139, 140] as well as those with T2D [155]

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A 2018 study found 5-amino-1MQ increased NAD+ by up to 40% in cultured adipocytes, but this cellular change precedes noticeable effects by weeks

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Biochemical Pharmacology (2019) 6