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Biomedicines 10(6):1448 Franceschi C, Campisi J (2014) Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases

doi: 10.1016/J.ENVINT.2023.108248 38

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(2000, 2004) [9,63] verified by CLSM images (Figure 10) that the skin penetration and accumulation of protoporphyrin IX, an endogenously photosensitizer obtained from 5-aminolevulinic acid (5-ALA) by the biosynthetic pathway of heme, depended on the presence of penetration enhancer substance in the vehicle and 5-ALA derivative used