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A study from the genomics and transcriptomics on Rhodococcus species suggests that 4-nitrophenol breaks down into acetyl-coA and succinate by nitrocatechol through Nph -specific genes (Miglani et al., could potentially facilitate effective detoxification of such undesirable metabolites and reduced accumulation of environmental contaminants, thus reducing biological and physiological complications

1c,d) and was previously suggested as a candidate for a potential activator site, first, because its positive charge might stabilize or bind GSH as GS , and, second, because of its evolutionary conserved position that is equivalent to the GSH-interacting catalytic residue of glutathione transferases 3

doi: 10.1007/s00125-020-05262-w 53 HoKKOSullivanAJHoffmanDM

It is extremely easily oxidized to disulfide bonds, forming inactive oxidized glutathione (GSSG)

Z., Wang, C