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Description

Evidence that human class Theta glutathione S-transferase T1-1 can catalyse the activation of dichloromethane, a liver and lung carcinogen in the mouse

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Patients (aged 18 years, BMI 18.5 kg/m) scheduled for living kidney transplantation were enrolled after written informed consent

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Confirmed overall response rate was 20% (95% CI = 11, 31) in the selumetinib arm compared to 5% (95% CI = 2, 13) for those receiving placebo (p = 0.011)

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No associations of fibrinolysis inhibitors changes with PC on treatment were found in either patient group

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