melanotic macuole macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Labial melanotic macule image

40 Frameshift, homozygous splicing, and nonsense mutations developed severe phenotypes of PFIC2

Mehrzad J, Fazel F, Pouyamehr N, Hosseinkhani S, Dehghani H

After the first clinical feasibility study demonstrated safe and promising outcomes in ECD using an EVMP system with a pediatric cardiopulmonary bypass technology (Medtronic) ( The LifePort Kidney Transporter can be used for both pulsatile and non-pulsatile perfusion at 1C5C and is portable with the possibility of unaccompanied transport, thus reducing logistical efforts and costs

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Timely diagnosis and individualized therapy are important to prevent long-term morbidity and improve patient outcomes

This is why its always important to discuss with your physician before adding any supplement to your diet