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C reaction for type 4, type 5 and type 6 isolates)

Butyrate enhances the efficacy of chemotherapeutic agents via two mechanisms: it inhibits tumor cell glycolysis (the Warburg effect), reducing energy supply and sensitizing cells to chemotherapy, and it activates the GPR109aAKT pathway, inducing cell cycle arrest and apoptosis, thereby increasing chemosensitivity (Geng et al., 2021)

Eurasian J Med 40:1 Azimi P, Ghiasvand R, Feizi A, Hosseinzadeh J, Bahreynian M, Hariri M, Khosravi-Boroujeni H (2016) Effect of cinnamon, cardamom, saffron and ginger consumption on blood pressure and a marker of endothelial function in patients with type 2 diabetes mellitus: a randomized controlled clinical trial

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doi: 10.1016/j.heliyon.2023.e18741 55

4-Nunca faa uso de medicamentos sem orientao de profissional habilitado