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Furthermore, inactivation of GSTA4 (HCT116 GSTA4 ) did not increase apoptosis compared with the parental HCT116 cells when treated with 5-FU (5 M) and oxaliplatin (5 M), suggesting that loss of GSTA4 augmented chemotherapeutic reduction of cell viability without affecting apoptosis

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Vitamin B12 supplementation may be helpful for people at risk of deficiency, such as those on vegan diets, patients with certain gastrointestinal conditions, or those taking metformin