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A., Jambusaria-Pahlajani, A., Ruiz, E

MDR1, also known as permeability glycoprotein ( P-gp ), is a transmembrane transport protein that recognizes and controls drug efflux from tumor tissues and eventually promotes drug resistance in breast cancer by altering drug distribution in tumors 52

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While this gliotoxin oxidase activity cannot be ruled out completely, our demonstration that GliT exhibits gliotoxin reductase activity (Figure 5) suggests that direct gliotoxin reduction is a pre-requisite for secretion from A

Baumann M, et al

Fibronectin aggregation in multiple sclerosis lesions impairs remyelination