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While in principle this condition leads to higher signal at any photon arrival time, higher sensitivity, and better spatial resolution 45 , in practice the benefits must be weighted against the stronger impact of the IRF on the detected signal due the the overwhelming burst of early photons

It crosses the blood-brain barrier and activates the hepatocyte growth factor (HGF) / c-Met receptor pathway, a signaling system that governs neuron survival, synaptic formation, and neural circuit repair

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