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Carbohydrate utilization by the Lyme borreliosis spirochete, Borrelia burgdorferi

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Lim, D., Ronco, V., Grolla, A

doi: 10.1016/j.chembiol.2019.10.003 40 HuangY.YeZ.MaT.LiH.ZhaoY.ChenW.et al

These effects undermine mitochondrial integrity, facilitate the release of mitochondrial DNA (mtDNA), and trigger irreversible cuproptosis

Negative Feedback Loop During this process, as glutathione is produced, there is a negative feedback loop