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Within this cycle, astrocytes uptake synaptic glutamate and GABA, enzymatically converting glutamate and ammonia to glutamine via GS

pmid:10512854 Bickel PE, Scherer PE, Schnitzer JE, Oh P, Lisanti MP, Lodish HF (1997) Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins

This is achieved by transporting glutamate to the mitochondrial matrix through a mitochondrial aspartate/glutamate carrier aralar [91, 92]

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After 28 days of saffron treatment, behavioral testing targeting anxiety, nociception, motor coordination, and cognition showed an amelioration of autism-like behaviors

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