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It could be speculated that the altered methylation status of this gene, as opposed to Gnrh or Kiss1 , might be subtle enough for the reproductive system both to sense and tolerate without implementing compensatory mechanisms to overcome it, allowing SRD5A1 to function in this context

Schwartz, M

Epithalon binds promoter regions of retinal genes F379, telomerase, and RNA polymerase II

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DSIP differs from more pathway-specific compounds such as Epitalon and Orexin in that it does not act through a single defined receptor or molecular axis

We hypothesised that the telomere length elongation seen in the cancer cell lines may be due to ALT activity