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Early proactive monitoring of DNA-thioguanine in patients with Crohns disease predicts thiopurine-induced late leucopenia in NUDT15/TPMT normal metabolizers

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as the bioavailability ( F ) of theophylline is only 0.6, the administered dose needs to be 232/0.6 = 387 mg (Answer C)

Additionally, the microfluidic systems can integrate many channels, so that various fluid phases can simultaneously flow in the systems

10.1016/S1474-4422(14)70090-0 Lancet Neurol