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In Step 3, phosphate enters the active site and, in a phosphorylase reaction, cleaves the carbonsulfur bond, displacing the 3-phosphoglycerate group, producing 1,3-bisphosphoglycerate and regenerating the sulfhydryl group

The role of mtROS in host-pathogen interactions extends to Pseudomonas aeruginosa , where quorum-sensing molecules induce mitochondrial depolarization and oxidative stress, contributing to tissue injury in chronic lung infections ( 3.5 Bacteria-induced mtDNA release and activation of innate immune Mitochondrial damage induced by bacterial effectors often results in mtDNA leakage into the cytosol or extracellular environment

Hypoxia-inducible factor-1: Regulatory mechanisms and drug development in stroke

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The primate basal ganglia: parallel and integrative networks