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However, when the oxidant level exceeds the reducing abilities of cells, ROS can lead to cellular damage through the oxidation of biomolecules, such as proteins, lipids, and DNA [8]

In support of the latter, it is noteworthy that the addition of rotenone, potent inhibitors of complex I of mETC [50], to CHO cells showed modest collateral sensitivity, significantly less than tamoxifen alone (supplemental Fig

Furthermore, the interplay between ferroptosis and other cell death pathways requires deeper investigation to design rational combination strategies

lactis based on WGS data and an overall genome related index (OGRI) [82]

Biochem Biophys Res Commun (2003) 307(4):102937.10.1016/S0006-291X(03)01292-0 111 Lee-HuangSHuangPLZhangDLeeJWBaoJSunYet alDiscovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I