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Inspection of heatmaps (produced with hierarchical clustering) revealed that expression of tagged wild-type FUS/TLS rescued the majority of splicing events that resulted from endogenous FUS/TLS reduction, yielding a pattern more similar to the parental cells (Fig

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GLS is frequently overexpressed in various types of cancer, including TNBC, NSCLC, and acute myeloid leukemia ( Therefore, inhibiting Gln degradation by downregulating the expression of these enzymes may represent a novel strategy for cancer treatment

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