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Add ice-cold 5 % MPA (~1 mL/100 mg tissue) and homogenize using a glass pestle

In a cervical cancer cell line (HeLa), the compound reduced cell proliferation in a concentration- and time-dependent way and lowered expression of phospho-Akt and SIRT1, two proteins tied to tumor progression, while a non-cancer reference cell line was less affected

Hepatocellular carcinoma treatment: hurdles, advances and prospects

Formal guidelines: management of acute respiratory distress syndrome

A Chi-square test was used to compare comorbidities, and a Wilcoxon rank sum test or Welchs t-test was used to compare age, as shown in the results section (propensity score matching)

Consequently, further research is necessary to elucidate the conditions under which these enzymes preferentially facilitate lactylation over other acylation processes