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Aspartate may be combined with citrulline by argininosuccinate synthase to form argininosuccinate, which is converted to L-arginine and fumarate by argininosuccinate lyase

30, 3747.10.1016/0169-328X(94)00273-H 36 EckertJ

Oct 2023;9(5):698-703

The second exception is when a bovine is apparently very sick from either a gut disorder that may have wreaked havoc on their rumen microbial communities (like what acidosis can do) or are suffering from serious cobalt/B12 deficiency

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Ketone bodies can serve as an alternative energy substrate for the brain, bypassing the glycolytic pathway and directly entering the citric acid cycle to produce ATP