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This allowed for multivalent binding to the EGFR receptor, overexpressed on inflammatory breast cancer (IBC) cells, and ultimately enabled the delivery of the enzyme intracellularly

In the face of controversies and challenges, it is essential to establish a more efficient translational interface between science, technology, and clinical practice, driving mitochondrial metabolic reprogramming therapy from a potential pathway to clinical reality. Conclusion Mitochondrial metabolic reprogramming plays a central role in the therapeutic failure of CRC

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Avoid direct contact with the peptide or solvent using bare hands

Front Microbiol 13

Thus, the dosage in individual cases was modulated to avoid the occurrence of specific clinical side effects or blood exam abnormalities (headache and insomnia, weight changes, age, neutropenia, alteration of liver function indices, hypercholesterolemia, gastrointestinal disturbances) by adjusting to maximal dosage without side effects, as required for off-label drug administration