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Immunity 38 (2), 225236 (2013)

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Th1 cells and Th2 cells consume arginine for polyamine synthesis at much higher rates than Th17 cells and Treg cells, suggesting that Th17 cells and Treg cells use different substrates for polyamine synthesis from Th1 cells and Th2 cells [244]

Am J Kidney Dis 2013;62(2):395

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Use the lowest effective dose for the shortest time needed , especially for NSAIDs and in older adults who face higher risks from both medications