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Nature 628 , 4756 (2024)

During preclinical research, Vorinostat therapy increased levels of ROS in malignant cells, resulting in increased cell death and decreased tumor cell proliferation (144)

Particularly, atorvastatin can be used as an adjuvant treatment in addition to decreasing cholesterol

Conceptually, a metabolic reprogramming agent potentiates the efficacy of an antibiotic in the same manner as an adjuvant potentiates the immunogenicity of an antigen