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Studies have estimated that GHK levels may decrease by more than 50% between early adulthood and later life

E., Flores, K

BV-2 cells were subsequently treated with various concentrations (2, 20, 50 mol/L) of acetaminophen (MP Biomedicals, Solon, OH, USA), p-aminophenol (Sigma-Aldrich), AM404 (Cayman), or vehicle solution (0.1% DMSO) and incubated for a further 15 min period under the same conditions

PLoS One 8 , e66808 (2013)

mechanical ventilation and vascular interventions such as central venous catheterization may further induce vascular endothelial damage in severe or critically ill patients

doi: 10.1055/s-0029-1241843 86 KapciskaBJagszSSadowska-KrepaEGrskiJKempaKLangfortJ