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Future validation of the results in independent population will need to be assessed for independent samples of HCC cases and controls

References: [1] KAI FU

Materials and methods Reagents Bromopyruvic acid (S5426), cetuximab (A2000), Compound C (S7840), and U0126 (S1102) were purchased from Selleck (Houston, TX, USA)

Sox2 fl / fl mice (Fig 2A and C) or ablating SOX2 + cells using diphtheria toxin (DTA) expressed under the control of the inducible Sox2 promoter ( Sox2 CreERT2 ;Rosa26 DTA