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While H 2 O 2 and superoxide are certainly capable of effecting unwanted oxidations, it is the hydroxyl radical that is the key

doi: 10.4239/wjd.v6.i4.548 [DOI] [PMC free article] [PubMed] [Google Scholar]

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Proline is exceptional in that it has an R group that folds back and covalently bonds to the backbone of the amino acid, creating a more rigid element in a protein chain that reduces free movement of the polypeptide chain