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Autologous cells present a low risk of immune rejection but involve complex harvesting procedures, whereas allogeneic cells also carry a relatively low immunological risk owing to the immune-privileged nature of intervertebral discs, in addition to offering the advantage of scalable production ( 9.4 Number of transplanted cells In existing studies, the number of cells injected per disc ranges from 1 10 6 to 132 10 6 , and the optimal dose has not reached a consensus

IEEE Transactions on Neural Networks and Learning Systems, 31(5), 1544-1556

[DOI] [PMC free article] [PubMed] [Google Scholar] 223.Sun W., Wang X., Hou C., Yang L., Li H., Guo J

69 : 91579159v

10.47363/jnsrr/2022(4)141 64 RodriguesV

Delivery method also plays a role