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The findings highlight that ROS drive prostate cancer progression through multiple mechanisms, including altering the tumor microenvironment, activating the unfolded protein response (UPR), and regulating miRNA expression

Spermidines ability to modulate key signalling pathways involved in cellular longevity, combined with its accessibility through dietary sources and supplementation, supports its growing popularity as an anti-ageing nutraceutical

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Despite their low frequency, novel associations between rare neoplasms and hereditary conditions continue to emerge, although a solid association is often lacking

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For children aged 114 years the PRIs increase with age from 0.6 to 1.4 mg/day